Since the early works of scholars like Alexis Kagame and Placide Tempels, discussions on the concept of vitality in African philosophy have acquired many dimensions. With scholars like Noah Dzobo and Thaddeus Metz projecting it as a grounding for human values and dignity, Aribiah Attoe and Yolanda Mlungwana each exploring vitalist conceptions of meaning in life, and Ada Agada approaching vitality from a proto-panpsychist/consolationist perspective. Indeed, vitality features as an important concept in African philosophy of religion. This Element contributes to the discourse on vitality in African philosophy of religion by providing a critical overview of some traditional interpretations of the concept from the Bantu, Yoruba, and Igbo religious/philosophical worldviews. Furthermore, it explores how the concept of vitality features in discussions of ethics, dignity, and meaning in life. Finally, the Element provides a critique of the concept based on the interventions of Innocent Asouzu, Metz, and Bernard Matolino.